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51.
Fangyuan Zhou Lesong Li Kao Lin Feng Zhang Prof. Dr. Guo-Jun Deng Dr. Hang Gong 《Chemistry (Weinheim an der Bergstrasse, Germany)》2020,26(19):4246-4250
The radical–radical coupling reaction is an important synthetic strategy. In this study, the iron-catalyzed radical–radical cross-coupling reaction based on the decarboxylation of keto acids and decarbonylation of aliphatic aldehydes to obtain valuable aryl ketones is reported for the first time. Remarkably, when tertiary aldehydes were used as carbonyl sources, ketone esters were selectively obtained instead of ketones. The gram-scale preparation of aryl ketone through this strategy was easily achieved by using only 3 mol % of the iron catalyst. As a proof-of-concept, the bioactive molecule flurprimidol was synthesized in two steps by using this strategy. 相似文献
52.
Honghua Zhang Huihong Wang Yi Jiang Fei Cao Weiwei Gao Longqing Zhu Yuhang Yang Xiaodong Wang Yongqiang Wang Jinhong Chen Yiyue Feng Xuemei Deng Yingmei Lu Xiaoling Hu Xiangxiang Li Juan Zhang Tao Shi Prof. Zhen Wang 《Chemistry (Weinheim an der Bergstrasse, Germany)》2020,26(72):17289-17317
Sulfur-containing scaffold, as a ubiquitous structural motif, has been frequently used in natural products, bioactive chemicals and pharmaceuticals, particularly C−S/N−S bonds are indispensable in many biological important compounds and pharmaceuticals. Development of mild and general methods for C−S/N−S bonds formation has great significance in modern research. Iodine and its derivatives have been recognized as inexpensive, environmentally benign and easy-handled catalysts or reagents to promote the construction of C−S/N−S bonds under mild reaction conditions, with good regioselectivities and broad substrate scope. Especially based on this, several new strategies, such as oxidation relay strategy, have been greatly developed and accelerated the advancement of this field. This review focuses on recent advances in iodine and its derivatives promoted hybridized C−S/N−S bonds formation. The features and mechanisms of corresponding reactions are summarized and the results of some cases are compared with those of previous reports. In addition, the future of this domain is discussed. 相似文献
53.
54.
Hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) have been deemed as clean and sustainable strategies to solve the energy crisis and environmental problems. Various catalysts have been developed to promote the process of HER and OER. Among them, two-dimensional covalent organic frameworks (2D COFs) have received great attention due to their diverse and designable structure. In this minireview, we mainly summarize the diverse linkages of 2D COFs and strategies for enhancing the catalytic performance of 2D COFs for HER and OER, such as introducing active building blocks, metal ions and tailored linkages. Furthermore, a brief outlook for the development directions of COFs in the field of HER and OER is provided, expecting to stimulate new opportunities in future research. 相似文献
55.
Cao Hongmei Deng Shenzhen Tie Zhiwei Tian Jinlei Liu Lili Niu Zhiqiang 《中国科学:化学(英文版)》2022,65(9):1725-1732
Science China Chemistry - Synchronously reducing/self-assembling strategy on Zn substrate was designed to fabricate large-area cation-doped hydrated V2O5/multi-walled carbon nanotube (D-HVO/MWCNT)... 相似文献
56.
Liu Wei Li Kehong Deng Hao Wang Jing Zhao Peng Liao Wei Zhuo Liangang Wei Hongyuan Yang Xia Chen Yue 《Journal of Radioanalytical and Nuclear Chemistry》2022,331(2):747-754
Journal of Radioanalytical and Nuclear Chemistry - There is an urgent need to develop more specific targeted therapies for lung cancer treatment due to the its low survival rate. EGFR is a... 相似文献
57.
Wei-Qi Deng 《Numerical Algorithms》2014,67(2):243-256
The main purpose in this paper is to introduce an original technique, namely, a specific way of choosing the indexes of the involved operators, by which a new iterative algorithm is developed for solving the split common fixed point problem for infinite families of total quasi-asymptotically nonexpansive operators and some strong and weak convergence theorems are established for this class of nonlinear operators in the framework of infinite-dimensional Hilbert spaces. The result is more applicable than those of other authors with related interest. 相似文献
58.
Shuai Zhao Prof. Shaohua Zhang Huijun Hu Yangchang Cheng Kexuan Zou Prof. Jie Song Dr. Jinqi Deng Prof. Lele Li Prof. Xiao-Bing Zhang Prof. Guoliang Ke Prof. Jiashu Sun 《Angewandte Chemie (International ed. in English)》2023,62(24):e202303121
Mature microRNAs (miRNAs) in extracellular vesicles (EVs) are involved in different stages of cancer progression, yet it remains challenging to precisely detect mature miRNAs in EVs due to the presence of interfering RNAs (such as longer precursor miRNAs, pre-miRNAs) and the low abundance of tumor-associated miRNAs. By leveraging the size-selective ability of DNA cages and polyethylene glycol (PEG)-enhanced thermophoretic accumulation of EVs, we devised a DNA cage-based thermophoretic assay for highly sensitive, selective, and in situ detection of mature miRNAs in EVs with a low limit of detection (LoD) of 2.05 fM. Our assay can profile EV mature miRNAs directly in serum samples without the interference of pre-miRNAs and the need for ultracentrifugation. A clinical study showed that EV miR-21 or miR-155 had an overall accuracy of 90 % for discrimination between breast cancer patients and healthy donors, which outperformed conventional molecular probes detecting both mature miRNAs and pre-miRNAs. We envision that our assay can advance EV miRNA-based diagnosis of cancer. 相似文献
59.
Shuang Qiu Wannan Li Tao Deng Angzhi Bi Yang Yang Xi Jiang Dr. Jie P. Li 《Angewandte Chemie (International ed. in English)》2023,62(28):e202303014
Intercellular proximity labeling has emerged as a promising approach to enable the study of cell-cell interactions (CCIs), but the efficiency of current platforms is limited. Here, we use Ru(bpy)32+ to construct an efficient photocatalytic proximity labeling (PPL) system on the cell surface that allows the highly discriminative CCI detection with spatiotemporal resolution. Through the mechanism study and quantitative characterization on living cells, we demonstrate that the singlet-oxygen (1O2) mechanism is more efficient and specific than the single electron transfer (SET) mechanism in Ru-mediated PPL. Ru(bpy)32+ catalysts with different cell-anchoring moieties are prepared to facilitate the catalyst loading on primary cells. Finally, based on this system, we develop a “live” T cell receptor (TCR) multimer with TCR-T cells that could sensitively identify and discriminate cells presenting antigens of different affinity, providing a powerful tool to better understand the heterogeneity of antigen presenting cells. 相似文献
60.
Ye Qian Mi Wei Deng Chaohui He Prof. Dr. Osman Eksik Yi Ping Zheng De Kun Yao Dr. Xian Bin Liu Yan Hong Yin Ye Sheng Li Prof. Dr. Bao Yu Xia Prof. Dr. Zi Ping Wu 《Angewandte Chemie (International ed. in English)》2023,62(12):e202218621
Solid-state lithium batteries are promising and safe energy storage devices for mobile electronics and electric vehicles. In this work, we report a facile in situ polymerization of 1,3-dioxolane electrolytes to fabricate integrated solid-state lithium batteries. The in situ polymerization and formation of solid-state dioxolane electrolytes on interconnected carbon nanotubes (CNTs) and active materials is the key to realizing a high-performance battery with excellent interfacial contact among CNTs, active materials and electrolytes. Therefore, the electrodes could be tightly integrated into batteries through the CNTs and electrolyte. Electrons/ions enable full access to active materials in the whole electrode. Electrodes with a low resistance of 4.5 Ω □−1 and high lithium-ion diffusion efficiency of 2.5×10−11 cm2 s−1 can significantly improve the electrochemical kinetics. Subsequently, the batteries demonstrated high energy density, amazing charge/discharge rate and long cycle life. 相似文献